Transient genotype - environment interactions following environmental shock provide a source of expression variation for essential genes ”
نویسندگان
چکیده
Microarray data from this article have been deposited with the NIH GEO Data Base under accession number GSE15147 ABSTRACT Understanding complex genotype-by-environment interactions (GEI) is crucial for understanding phenotypic variation. An important factor often overlooked in GEI studies is time. We measured the contribution of GEI to expression variation in 4 non-laboratory S. cerevisiae strains responding gene expression compared to the average yeast gene, whereas genes restricted to transient GEI did not. We propose that transient GEI during the transition between environments provides a previously unappreciated source of expression variation, particularly for essential genes.
منابع مشابه
Transient genotype-by-environment interactions following environmental shock provide a source of expression variation for essential genes.
Understanding complex genotype-by-environment interactions (GEIs) is crucial for understanding phenotypic variation. An important factor often overlooked in GEI studies is time. We measured the contribution of GEIs to expression variation in four nonlaboratory Saccharomyces cerevisiae strains responding dynamically to a 25 degrees -37 degrees heat shock. GEI was a major force explaining express...
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